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  5. A composition comprising a compound of claim 2, or a pharmaceutically acceptable salt
  thereof, and a pharmaceutically acceptable carrier, diluent,
  or excipient. 4. A composition comprising a compound of claim 1, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier,
  diluent, or excipient. Another aspect of the invention is a compound of formula I where Ar.sup.2
  is -1,4-substituted with respect to the nitrogen and the
  Ar.sup.3 to which it is attached. Ar.sup.1 is phenyl, pyridinyl,
  pyridazinyl, pyrimidinyl, pyrazinyl, pyrrolyl, furanyl,
  thienyl, pyrazolyl, isoxazolyl, isothiazolyl, imidazolyl, oxazolyl,
  thiazolyl, triazinyl, oxadiazolyl, thiadiazolyl, or benzodioxyl, and is substituted with 1-3
  substituents selected from cyano, halo, alkyl, haloalkyl,
  alkoxy, haloalkoxy, alkylthio, and SO.sub.2R.sup.6; Ar.sup.2 is phenyl, pyridinyl, pyridazinyl, pyrimidinyl,
  or pyrazinyl, and is substituted with 0-3 substituents selected from
  cyano, halo, alkyl, haloalkyl, alkoxy, and haloalkoxy; Ar.sup.3 is aryl or heteroaryl, and is
  substituted with 0-3 substituents selected from cyano,
  halo, alkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, (NR.sup.1R.sup.2)alkyl, (CO.sub.2R.sup.3)alkyl, (CONR.sup.4R.sup.5)alkyl, (SO.sub.2R.sup.6)alkyl, hydroxy, alkoxy, haloalkoxy,
  cycloalkoxy, NR.sup.1R.sup.2, CO.sub.2R.sup.3, CONR.sup.4R.sup.5, SO.sub.2R.sup.6, Oxo, aryl, and
  heteroaryl; R.sup.1 is hydrogen, alkyl, alkylcarbonyl, alkylsulfonyl, or haloalkylsulfonyl;
  R.sup.2 is hydrogen or alkyl; or NR.sup.1R.sup.2 taken together is selected from azetidinyl,
  pyrrolidinyl, piperidinyl, piperazinyl, and morpholinyl, and is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, alkoxy, and haloalkoxy;
  and R.sup.3 is alkyl or haloalkyl; R.sup.4 is hydrogen, alkyl, or (R.sup.7R.sup.8N)alkyl;
  R.sup.5 is hydrogen or alkyl; or NR.sup.4R.sup.5 taken together is
  selected from azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl,
  and morpholinyl, and is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl,
  alkoxy, and haloalkoxy; R.sup.6 is alkyl or R.sup.7R.sup.8N; R.sup.7 is hydrogen or
  alkyl; R.sup.8 is hydrogen or alkyl; or NR.sup.7R.sup.8 taken together is selected from azetidinyl,
  pyrrolidinyl, piperidinyl, piperazinyl, and morpholinyl,
  and is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, alkoxy, and haloalkoxy;
  and X is hydrogen, halo, hydroxy, or alkoxy; or a pharmaceutically acceptable salt thereof.
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